全部产品分类
品牌 |
Leading Biology | 货号 |
APR09158G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Phospho-Caspase-6 (Ser257) antibody.
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分子量 |
33310 Da
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细胞定位 |
Antigen Cellular Localization:
Cytoplasm.
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宿主 |
Rabbit
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种属反应性 |
Human, Mouse, Rat
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靶点 |
Caspase-6 (Ser257)
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亚型 |
Rabbit IgG
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通用名 |
MCH2
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基因ID |
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UniProt ID |
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功能 |
Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly(ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death.
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总结 |
Caspases are the central components of the apoptotic response. Caspase 6 is a member of the cysteine-aspartic acid protease (caspase) family. Caspases are divided into two classes: the initiator caspases, which include caspase 2, 8, 9 and 10 and the effector caspases, which include caspases 3, 6 and 7. Effector caspases being activated by initiator caspases leads the proteolytic cleavage of a broad spectrum of cellular targets, which ultimately leads to cell death.
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形式 |
100ug (1mg/ml) of antibody in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC, IF
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别名 |
CASP6; MCH2; Caspase-6; CASP-6; Apoptotic protease Mch-2
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图像 |
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说明书 |
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数量 |
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