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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Polyclonal Antibodies > GABARAPL2 / ATG8 Antibody (C-Terminus)

GABARAPL2 / ATG8 Antibody (C-Terminus)

货号 货期 规格 / 价格 询价
AMM04654G 50 μg / ¥4950

GABARAPL2 / ATG8 Antibody (C-Terminus)

品牌

Leading Biology

货号

AMM04654G

产品分类

Polyclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality GABARAPL2 / ATG8 antibody (C-Terminus).

分子量

13667 Da

细胞定位

Antigen Cellular Localization: Golgi apparatus. Cytoplasmic vesicle, autophagosome

宿主

Rabbit

种属反应性

Human, Mouse, Rat

靶点

GABARAPL2 antibody is human, mouse and rat reactive. Multiple isoforms of GABARAPL2 are known to exist.

通用名

FLC3A, GEF2

基因ID

UniProt ID

功能

Ubiquitin-like modifier involved in intra-Golgi traffic. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1 (By similarity). Involved in autophagy. Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation.

总结

Ubiquitin-like modifier involved in intra-Golgi traffic. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1 (By similarity). Involved in autophagy. Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation.

形式

Liquid

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

WB, IHC-P, IF, E

稀释方法

IF (20 μg/ml), IHC-P (10 μg/ml), WB (1 - 2 μg/ml),

别名

GABARAPL2, ATG8, ATG8C, GEF2, FLC3A, GATE-16, GATE16, GEF-2

图像

Immunohistochemistry of GABARAPL2 in rat brain tissue with GABARAPL2 antibody at 5 ug/mL.

Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)

Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)

说明书

数量

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