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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Polyclonal Antibodies > KCNMB4 Antibody (aa86-140)

KCNMB4 Antibody (aa86-140)

货号 货期 规格 / 价格 询价
AMM06158G 50 μl / ¥4950

KCNMB4 Antibody (aa86-140)

品牌

Leading Biology

货号

AMM06158G

产品分类

Polyclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality KCNMB4 antibody (aa86-140).

分子量

23949 Da

细胞定位

Antigen Cellular Localization: Membrane; Multi-pass membrane protein.

宿主

Rabbit

种属反应性

Human, Mouse, Rat

靶点

Human KCNMB4

基因ID

UniProt ID

功能

Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Decreases the gating kinetics and calcium sensitivity of the KCNMA1 channel, but with fast deactivation kinetics. May decrease KCNMA1 channel openings at low calcium concentrations but increases channel openings at high calcium concentrations. Makes KCNMA1 channel resistant to 100 nM charybdotoxin (CTX) toxin concentrations.

总结

Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Decreases the gating kinetics and calcium sensitivity of the KCNMA1 channel, but with fast deactivation kinetics. May decrease KCNMA1 channel openings at low calcium concentrations but increases channel openings at high calcium concentrations. Makes KCNMA1 channel resistant to 100 nM charybdotoxin (CTX) toxin concentrations.

形式

Liquid. In PBS containing 0.02% sodium azide.

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

WB, IHC-P

稀释方法

IHC-P (5 μg/ml), WB (1:500 - 1:1000),

别名

KCNMB4, BK beta 4, BK channel subunit beta-4, BKbeta4, Hbeta4, K(VCA)beta-4, Slowpoke beta 4, Maxi K channel subunit beta-4, Maxi K beta 4, Slo-beta-4

图像

Anti-KCNMB2 antibody IHC staining of human brain, cortex.

Human Vascular Smooth Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE)

Western blot of MaxiK (K119) pAb in extracts from HepG2 cells.

说明书

数量

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