品牌 |
Leading Biology | 货号 |
APR08091G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality KIAA0101 antibody.
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分子量 |
12kDa
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细胞定位 |
Antigen Cellular Localization:
Nucleus. Cytoplasm, perinuclear region. Note=Following DNA damage, localizes to DNA damage sites Colocalizes with centrosomes in perinuclear region
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宿主 |
Rabbit
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种属反应性 |
Human
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靶点 |
Human KIAA0101
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通用名 |
NS5ATP9, PAF
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基因ID |
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UniProt ID |
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功能 |
PCNA-binding protein that acts as a regulator of DNA repair during DNA replication. Following DNA damage, the interaction with PCNA is disrupted, facilitating the interaction between monoubiquitinated PCNA and the translesion DNA synthesis DNA polymerase eta (POLH) at stalled replisomes, facilitating the bypass of replication-fork-blocking lesions. Also acts as a regulator of centrosome number.
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总结 |
PCNA-binding protein that acts as a regulator of DNA repair during DNA replication. Following DNA damage, the interaction with PCNA is disrupted, facilitating the interaction between monoubiquitinated PCNA and the translesion DNA synthesis DNA polymerase eta (POLH) at stalled replisomes, facilitating the bypass of replication-fork-blocking lesions. Also acts as a regulator of centrosome number.
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形式 |
Liquid
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
IHC-P
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稀释方法 |
IHC-P (10 μg/ml)
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别名 |
PCNA-associated factor, Hepatitis C virus NS5A-transactivated protein 9, HCV NS5A-transactivated protein 9, Overexpressed in anaplastic thyroid carcinoma 1, OEATC-1, PCNA-associated factor of 15 kDa, PAF15, p15PAF, KIAA0101, NS5ATP9, PAF
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图像 |
Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE) |
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说明书 |
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数量 |
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