全部产品分类
品牌 |
Leading Biology | 货号 |
APR17301G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality MAPK6 / ERK3 antibody (C-Terminus).
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分子量 |
83kDa
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细胞定位 |
Antigen Cellular Localization:
Cytoplasm. Nucleus. Note=Translocates to the cytoplasm following interaction with MAPKAPK5.
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宿主 |
Goat
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种属反应性 |
Human, Mouse, Rabbit, Hamster, Pig, Chicken, Horse, Bovine, Dog
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靶点 |
Human MAPK6 / ERK3. Reported variants represent identical protein (NP_056621.4; NP_081694.1).
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通用名 |
ERK3, PRKM6
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基因ID |
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UniProt ID |
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功能 |
Atypical MAPK protein. Phosphorylates microtubule- associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK3/MAPK6 is phosphorylated at Ser-189 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK3/MAPK6. May promote entry in the cell cycle (By similarity).
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总结 |
Atypical MAPK protein. Phosphorylates microtubule- associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK3/MAPK6 is phosphorylated at Ser-189 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK3/MAPK6. May promote entry in the cell cycle (By similarity).
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形式 |
Liquid
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P, E
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稀释方法 |
ELISA (1:128000), IHC-P (10 μg/ml), WB (0.5-1 μg/ml)
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别名 |
Mitogen-activated protein kinase 6, MAP kinase 6, MAPK 6, 2.7.11.24, Extracellular signal-regulated kinase 3, ERK-3, MAP kinase isoform p97, p97-MAPK, MAPK6, ERK3, PRKM6
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图像 |
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说明书 |
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数量 |
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