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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Polyclonal Antibodies > CRHR2 / CRF2 Receptor Antibody (aa71-120)

CRHR2 / CRF2 Receptor Antibody (aa71-120)

货号 货期 规格 / 价格 询价
APR11667G 50 μl / ¥4950

CRHR2 / CRF2 Receptor Antibody (aa71-120)

品牌

Leading Biology

货号

APR11667G

产品分类

Polyclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CRHR2 / CRF2 Receptor antibody (aa71-120).

分子量

48kDa

细胞定位

Antigen Cellular Localization: Cell membrane; Multi-pass membrane protein

宿主

Rabbit

种属反应性

Human, Mouse, Rat

靶点

CRFR2 Antibody detects endogenous levels of total CRFR2 protein.

通用名

CRF2R, CRH2R

基因ID

UniProt ID

功能

G-protein coupled receptor for CRH (corticotropin- releasing factor), UCN (urocortin), UCN2 and UCN3. Has high affinity for UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels.

总结

G-protein coupled receptor for CRH (corticotropin- releasing factor), UCN (urocortin), UCN2 and UCN3. Has high affinity for UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels.

形式

Liquid. In PBS containing 0.02% sodium azide.

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

WB, IHC-P, E

稀释方法

ELISA (1:10000), IHC-P (10 μg/ml), WB (1:500-1:1000)

别名

Corticotropin-releasing factor receptor 2, CRF-R-2, CRF-R2, CRFR-2, Corticotropin-releasing hormone receptor 2, CRH-R-2, CRH-R2, CRHR2, CRF2R, CRH2R

图像

Anti-CRHR2 / CRF2 Receptor antibody IHC staining of human adrenal.

Western blot of extracts from K562/LOVO/NIH-3T3/RAW264.7 cells, using CRFR2 Antibody.

说明书

数量

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