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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Monoclonal Antibodies > KCNJ4 / Kir2.3 Antibody (aa390-445, clone S25-35)

KCNJ4 / Kir2.3 Antibody (aa390-445, clone S25-35)

货号 货期 规格 / 价格 询价
AMM06128G 50 μg / ¥4950

KCNJ4 / Kir2.3 Antibody (aa390-445, clone S25-35)

品牌

Leading Biology

货号

AMM06128G

产品分类

Monoclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality KCNJ4 / Kir2.3 antibody (aa390-445, clone S25-35).

分子量

50kDa

细胞定位

Antigen Cellular Localization: Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane. Note=TAX1BP3 binding promotes dissociation of KCNJ4 from LIN7 famaly members and KCNJ4 internalization

宿主

Mouse

种属反应性

Human, Mouse, Rat

靶点

Detects ~45 kD protein. No cross reactivity against Kir2.1, or Kir2.2.

克隆号

S25-35

通用名

IRK3

基因ID

UniProt ID

功能

Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium (By similarity).

总结

Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium (By similarity).

形式

Liquid

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

WB, IHC-P, IF, ICC, IP

稀释方法

ICC (0.1-1 μg/ml), IHC-P (5 μg/ml), IP (1-10 μg/ml), WB (1-10 μg/ml) ,

别名

Inward rectifier potassium channel 4, HIRK2, HRK1, Hippocampal inward rectifier, HIR, Inward rectifier K(+) channel Kir2.3, IRK-3, Potassium channel, inwardly rectifying subfamily J member 4, KCNJ4, IRK3

图像

Kir2.3 (S25-35), Human hippocampus.

Kir2 3 (S25-35), Human cell line mix.

Anti-KCNJ4 / Kir2.3 antibody IHC of human brain, cortex neurons.

说明书

数量

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