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> 抗原抗体、ELISA、WB > 一抗 > Monoclonal Antibodies > KCNJ12 / Kir2.2 Antibody (aa362-427, clone S124B-38)品牌 |
Leading Biology | 货号 |
AMM06101G |
产品分类 |
Monoclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality KCNJ12 / Kir2.2 antibody (aa362-427, clone S124B-38).
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分子量 |
49kDa
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细胞定位 |
Antigen Cellular Localization:
Membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein
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宿主 |
Mouse
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种属反应性 |
Human, Mouse, Rat
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靶点 |
Detects ~45 kD protein. No cross reactivity against Kir2.1, or Kir2.3.
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克隆号 |
S124B-38
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通用名 |
IRK2, KCNJN1
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基因ID |
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UniProt ID |
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功能 |
Inward rectifying potassium channel that is activated by phosphatidylinositol 4,5-bisphosphate and that probably participates in controlling the resting membrane potential in electrically excitable cells. Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.
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总结 |
Inward rectifying potassium channel that is activated by phosphatidylinositol 4,5-bisphosphate and that probably participates in controlling the resting membrane potential in electrically excitable cells. Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.
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形式 |
Liquid
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P, IF, ICC
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稀释方法 |
ICC (0.1-1 μg/ml), IHC-P (5 μg/ml), WB (1-10 μg/ml)
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别名 |
ATP-sensitive inward rectifier potassium channel 12, Inward rectifier K(+) channel Kir2.2, IRK-2, Inward rectifier K(+) channel Kir2.2v, Potassium channel, inwardly rectifying subfamily J member 12, KCNJ12, IRK2, KCNJN1
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图像 |
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说明书 |
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数量 |
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