全部产品分类
品牌 |
Leading Biology | 货号 |
APG02080G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality ATP11B antibody (N-Terminus).
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分子量 |
134kDa
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细胞定位 |
Antigen Cellular Localization:
Recycling endosome membrane; Multi-pass membrane protein. Early endosome. Endoplasmic reticulum. Golgi apparatus, trans-Golgi network. Note=Exit from the endoplasmic reticulum requires the presence of TMEM30A, but not TMEM30B. In the presence of TMEM30A, mainly located in recycling endosomes
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宿主 |
Rabbit
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种属反应性 |
Human, Mouse
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靶点 |
Human ATP11B
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通用名 |
ATPIF, ATPIR, KIAA0956
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基因ID |
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UniProt ID |
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功能 |
Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules (Probable). Involved in regulation of sensitivity to cisplatin; may contribute to secretory vesicle transport of cisplatin from Golgi to plasma membrane.
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总结 |
Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules (Probable). Involved in regulation of sensitivity to cisplatin; may contribute to secretory vesicle transport of cisplatin from Golgi to plasma membrane.
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形式 |
Liquid
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P, IF, ICC, E
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稀释方法 |
IHC-P (5 μg/ml), WB (1-2 μg/ml),
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别名 |
Probable phospholipid-transporting ATPase IF, 3.6.3.1, ATPase IR, ATPase class VI type 11B, P4-ATPase flippase complex alpha subunit ATP11B, ATP11B, ATPIF, ATPIR, KIAA0956
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图像 |
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说明书 |
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数量 |
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