全部产品分类
品牌 |
Leading Biology | 货号 |
APR15623G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CTMP / THEM4 antibody (Internal).
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分子量 |
27kDa
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细胞定位 |
Antigen Cellular Localization:
Cell membrane. Cell projection, ruffle membrane Cytoplasm. Mitochondrion. Mitochondrion inner membrane; Peripheral membrane protein Mitochondrion intermembrane space. Note=Released from the mitochondria into the cytosol in response to apoptotic stimuli
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宿主 |
Rabbit
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种属反应性 |
Human, Mouse, Rat
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靶点 |
Human THEM4
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通用名 |
CTMP
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基因ID |
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UniProt ID |
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功能 |
Has acyl-CoA thioesterase activity towards medium and long-chain (C14 to C18) fatty acyl-CoA substrates, and probably plays an role in mitochondrial fatty acid metabolism. Plays a role in the apoptotic process, possibly via its regulation of AKT1 activity. According to PubMed:11598301, inhibits AKT1 phosphorylation and activity. According to PubMed:17615157, enhances AKT1 activity by favoring its phosphorylation and translocation to plasma membrane.
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总结 |
Has acyl-CoA thioesterase activity towards medium and long-chain (C14 to C18) fatty acyl-CoA substrates, and probably plays an role in mitochondrial fatty acid metabolism. Plays a role in the apoptotic process, possibly via its regulation of AKT1 activity. According to PubMed:11598301, inhibits AKT1 phosphorylation and activity. According to PubMed:17615157, enhances AKT1 activity by favoring its phosphorylation and translocation to plasma membrane.
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形式 |
Liquid
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P, IF, E
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稀释方法 |
IHC-P (5 μg/ml), WB (1-2 μg/ml),
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别名 |
Acyl-coenzyme A thioesterase THEM4, Acyl-CoA thioesterase THEM4, 3.1.2.2, Carboxyl-terminal modulator protein, Thioesterase superfamily member 4, THEM4, CTMP
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图像 |
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说明书 |
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数量 |
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