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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Polyclonal Antibodies > BACE2 Antibody (C-Terminus)

BACE2 Antibody (C-Terminus)

货号 货期 规格 / 价格 询价
APR11500G 50 μg / ¥4950

BACE2 Antibody (C-Terminus)

品牌

Leading Biology

货号

APR11500G

产品分类

Polyclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality BACE2 antibody (C-Terminus).

分子量

56kDa

细胞定位

Antigen Cellular Localization: Membrane; Single-pass type I membrane protein. Golgi apparatus. Endoplasmic reticulum. Endosome. Cell surface

宿主

Rabbit

种属反应性

Human

靶点

peptide corresponding to amino acids near the carboxy terminus of human BACE2

通用名

AEPLC, ALP56, ASP21

基因ID

UniProt ID

功能

Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves APP, between residues 690 and 691, leading to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C- terminal fragment which is later released by gamma-secretase. It has also been shown that it can cleave APP between residues 671 and 672.

总结

Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves APP, between residues 690 and 691, leading to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C- terminal fragment which is later released by gamma-secretase. It has also been shown that it can cleave APP between residues 671 and 672.

形式

Liquid

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

WB, IHC-P

稀释方法

IHC-P (5 μg/ml), WB (0.5-1 μg/ml),

别名

Beta-secretase 2, 3.4.23.45, Aspartic-like protease 56 kDa, Aspartyl protease 1, ASP1, Asp 1, Beta-site amyloid precursor protein cleaving enzyme 2, Beta-site APP cleaving enzyme 2, Down region aspartic protease, DRAP, Memapsin-1, Membrane-associated aspartic protease 1, Theta-secretase, BACE2, AEPLC, ALP56, ASP21

图像

Western blot of BACE2 in human heart tissue lysate in the absence (A) or presence (B) of...

Anti-BACE2 antibody IHC of human pancreas.

说明书

数量

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