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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Polyclonal Antibodies > IRGM / LRG-47 Antibody (Internal)

IRGM / LRG-47 Antibody (Internal)

货号 货期 规格 / 价格 询价
APR08028G 50 μg / ¥4950

IRGM / LRG-47 Antibody (Internal)

品牌

Leading Biology

货号

APR08028G

产品分类

Polyclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality IRGM / LRG-47 antibody (Internal).

分子量

20kDa

细胞定位

Antigen Cellular Localization: Golgi apparatus membrane. Cell membrane. Cytoplasmic vesicle, phagosome membrane. Cytoplasmic vesicle, autophagosome membrane. Cell projection, phagocytic cup Note=Behaves like an integral membrane protein. Recruited to the plasma membrane around forming phagocytic cups, it remains associated with maturing autophagosomes. Preferentially associated with cis- and medial-Golgi.

宿主

Rabbit

种属反应性

Human, Mouse, Rat

通用名

IFI1, IRGM1, LRG47

基因ID

UniProt ID

功能

Putative GTPase which is required for clearance of acute protozoan and bacterial infections. Functions in innate immune response probably through regulation of autophagy. May regulate proinflammatory cytokine production and prevent endotoxemia upon infection. May also play a role in macrophages adhesion and motility (By similarity).

总结

Putative GTPase which is required for clearance of acute protozoan and bacterial infections. Functions in innate immune response probably through regulation of autophagy. May regulate proinflammatory cytokine production and prevent endotoxemia upon infection. May also play a role in macrophages adhesion and motility (By similarity).

形式

Liquid

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

WB, IHC-P, IF, E

稀释方法

IHC-P (5 μg/ml), WB (1-2 μg/ml),

别名

Immunity-related GTPase family M protein, 3.6.5.-, Immunity-related GTPase family M protein 1, Interferon-inducible protein 1, LPS-stimulated RAW 264.7 macrophage protein 47 homolog, LRG-47, IRGM, IFI1, IRGM1, LRG47

图像

Western blot of IRGM in human brain lysate with IRGM antibody at (A) 1 and (B) 2 ug/ml.

Immunofluorescence of IRGM in Human Brain cells with IRGM antibody at 20 ug/ml.

Anti-IRGM antibody IHC of human colon.

说明书

数量

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