全部产品分类
品牌 |
Leading Biology | 货号 |
APR17508G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality MYO5B / Myosin VB antibody (N-Terminus).
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分子量 |
214kDa
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细胞定位 |
Antigen Cellular Localization:
Cytoplasm {ECO:0000250|UniProtKB:P70569}.
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宿主 |
Rabbit
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种属反应性 |
Human, Mouse
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靶点 |
Synthetic peptide corresponding to N-terminal residues of human Myosin-5B (Myosin Vb).
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通用名 |
KIAA1119
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基因ID |
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UniProt ID |
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功能 |
May be involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation. Required in a complex with RAB11A and RAB11FIP2 for the transport of NPC1L1 to the plasma membrane. Together with RAB11A participates in CFTR trafficking to the plasma membrane and TF (transferrin) recycling in nonpolarized cells. Together with RAB11A and RAB8A participates in epithelial cell polarization. Together with RAB25 regulates transcytosis.
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总结 |
May be involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation. Required in a complex with RAB11A and RAB11FIP2 for the transport of NPC1L1 to the plasma membrane. Together with RAB11A participates in CFTR trafficking to the plasma membrane and TF (transferrin) recycling in nonpolarized cells. Together with RAB11A and RAB8A participates in epithelial cell polarization. Together with RAB25 regulates transcytosis.
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形式 |
Liquid
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P, E
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稀释方法 |
ELISA (1 μg/ml), IHC-P (2.5 μg/ml), WB (1 μg/ml)
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别名 |
Unconventional myosin-Vb, MYO5B, KIAA1119
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图像 |
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说明书 |
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数量 |
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