全部产品分类
品牌 |
Leading Biology | 货号 |
AMM07930G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SOCS4 antibody (C-Terminus).
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分子量 |
51kDa
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宿主 |
Rabbit
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种属反应性 |
Human
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靶点 |
Peptide from the C-terminus of human SOCS4
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通用名 |
SOCS7
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基因ID |
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UniProt ID |
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功能 |
SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. Substrate-recognition component of a SCF-like ECS (Elongin BC- CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Inhibits EGF signaling by mediating the degradation of the Tyr-phosphorylated EGF receptor/EGFR.
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总结 |
SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. Substrate-recognition component of a SCF-like ECS (Elongin BC- CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Inhibits EGF signaling by mediating the degradation of the Tyr-phosphorylated EGF receptor/EGFR.
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形式 |
Liquid
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P, IP
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稀释方法 |
IHC-P (10 μg/ml), IP (0.3-0.5 μg/10E6 cells), WB (0.5-2 μg/ml)
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别名 |
Suppressor of cytokine signaling 4, SOCS-4, Suppressor of cytokine signaling 7, SOCS-7, SOCS4, SOCS7
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图像 |
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说明书 |
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数量 |
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