全部产品分类
品牌 |
Leading Biology | 货号 |
APR07615G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality DOK1 antibody (C-Terminus).
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分子量 |
52kDa
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细胞定位 |
Antigen Cellular Localization:
Isoform 1: Cytoplasm. Nucleus.
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宿主 |
Rabbit
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种属反应性 |
Human
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靶点 |
peptide corresponding to amino acids near the carboxy terminus of human p62dok
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基因ID |
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UniProt ID |
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功能 |
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3.
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总结 |
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3.
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形式 |
Liquid
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P, IF, ICC
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稀释方法 |
IHC-P (5 μg/ml), WB (0.5-1 μg/ml),
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别名 |
Docking protein 1, Downstream of tyrosine kinase 1, p62(dok), pp62, DOK1
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图像 |
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说明书 |
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数量 |
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