全部产品分类
品牌 |
Leading Biology | 货号 |
AMR09781G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality RRM2B antibody (aa2-17).
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分子量 |
41kDa
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细胞定位 |
Antigen Cellular Localization:
Cytoplasm. Nucleus. Note=Translocates from cytoplasm to nucleus in response to DNA damage
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宿主 |
Rabbit
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种属反应性 |
Human
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靶点 |
synthetic peptide (GDPERPEAAGLDQDER) corresponding to amino acids 2 to 17 of human p53R2
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通用名 |
P53R2
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基因ID |
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UniProt ID |
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功能 |
Plays a pivotal role in cell survival by repairing damaged DNA in a p53/TP53-dependent manner. Supplies deoxyribonucleotides for DNA repair in cells arrested at G1 or G2. Contains an iron-tyrosyl free radical center required for catalysis. Forms an active ribonucleotide reductase (RNR) complex with RRM1 which is expressed both in resting and proliferating cells in response to DNA damage.
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总结 |
Plays a pivotal role in cell survival by repairing damaged DNA in a p53/TP53-dependent manner. Supplies deoxyribonucleotides for DNA repair in cells arrested at G1 or G2. Contains an iron-tyrosyl free radical center required for catalysis. Forms an active ribonucleotide reductase (RNR) complex with RRM1 which is expressed both in resting and proliferating cells in response to DNA damage.
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形式 |
Liquid
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P, IF
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稀释方法 |
IHC-P (2.5 μg/ml), WB (0.5-1 μg/ml),
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别名 |
Ribonucleoside-diphosphate reductase subunit M2 B, 1.17.4.1, TP53-inducible ribonucleotide reductase M2 B, p53-inducible ribonucleotide reductase small subunit 2-like protein, p53R2, RRM2B, P53R2
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图像 |
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说明书 |
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数量 |
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