品牌 |
Leading Biology | 货号 |
APR12301G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality GRM6 / MGLUR6 antibody (N-Terminus).
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分子量 |
95kDa
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细胞定位 |
Antigen Cellular Localization:
Cell membrane; Multi-pass membrane protein Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein. Cell projection, dendrite. Note=Subject to trafficking from the endoplasmic reticulum to the Golgi apparatus and then to the cell membrane
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宿主 |
Rabbit
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种属反应性 |
Human, Monkey
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靶点 |
Human GRM6 / MGLUR6. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
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通用名 |
GPRC1F, MGLUR6
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基因ID |
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UniProt ID |
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功能 |
G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity (By similarity). Signaling stimulates TRPM1 channel activity and Ca(2+) uptake. Required for normal vision.
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总结 |
G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity (By similarity). Signaling stimulates TRPM1 channel activity and Ca(2+) uptake. Required for normal vision.
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形式 |
Liquid
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
IHC-P
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稀释方法 |
IHC-P (5.6 μg/ml)
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别名 |
Metabotropic glutamate receptor 6, mGluR6, GRM6, GPRC1F, MGLUR6
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图像 |
Anti-GRM6 / MGLUR6 antibody APR12301G IHC of human eye, ganglion cells.
Anti-GRM6 / MGLUR6 antibody IHC of human Lung, Non-Small Cell Carcinoma. |
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说明书 |
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数量 |
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