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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Polyclonal Antibodies > DOCK2 Antibody (C-term)

DOCK2 Antibody (C-term)

货号 货期 规格 / 价格 询价
APC00107G 100 μl / ¥4950

DOCK2 Antibody (C-term)

品牌

Leading Biology

货号

APC00107G

产品分类

Polyclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality DOCK2 antibody (C-term).

分子量

H=212;M=212 KDa

细胞定位

Antigen Cellular Localization: Endomembrane system; Peripheral membrane protein. Cytoplasm, cytoskeleton. Note=Colocalizes with F-actin

宿主

Rabbit

种属反应性

Human

免疫原

1812-1846 aa

靶点

This DOCK2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1812-1846 amino acids from the C-terminal region of human DOCK2.

通用名

KIAA0209

基因ID

UniProt ID

功能

Involved in cytoskeletal rearrangements required for lymphocyte migration in response of chemokines. Activates RAC1 and RAC2, but not CDC42, by functioning as a guanine nucleotide exchange factor (GEF), which exchanges bound GDP for free GTP. May also participate in IL2 transcriptional activation via the activation of RAC2.

总结

Involved in cytoskeletal rearrangements required for lymphocyte migration in response of chemokines. Activates RAC1 and RAC2, but not CDC42, by functioning as a guanine nucleotide exchange factor (GEF), which exchanges bound GDP for free GTP. May also participate in IL2 transcriptional activation via the activation of RAC2.

形式

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

WB

稀释方法

WB~~1:1000

别名

Dedicator of cytokinesis protein 2, DOCK2, KIAA0209

图像

All lanes : Anti-DOCK2 Antibody (C-term) at 1:1000 dilution Lane 1: Jurkat whole cell lysates Lane 2: Raji whole cell lysates Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L),Peroxidase conjugated at 1/10000 dilution Predicted band size : 212 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

说明书

数量

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