品牌 |
Leading Biology | 货号 |
APC00107G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality DOCK2 antibody (C-term).
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分子量 |
H=212;M=212 KDa
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细胞定位 |
Antigen Cellular Localization:
Endomembrane system; Peripheral membrane protein. Cytoplasm, cytoskeleton. Note=Colocalizes with F-actin
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
1812-1846 aa
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靶点 |
This DOCK2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1812-1846 amino acids from the C-terminal region of human DOCK2.
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通用名 |
KIAA0209
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基因ID |
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UniProt ID |
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功能 |
Involved in cytoskeletal rearrangements required for lymphocyte migration in response of chemokines. Activates RAC1 and RAC2, but not CDC42, by functioning as a guanine nucleotide exchange factor (GEF), which exchanges bound GDP for free GTP. May also participate in IL2 transcriptional activation via the activation of RAC2.
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总结 |
Involved in cytoskeletal rearrangements required for lymphocyte migration in response of chemokines. Activates RAC1 and RAC2, but not CDC42, by functioning as a guanine nucleotide exchange factor (GEF), which exchanges bound GDP for free GTP. May also participate in IL2 transcriptional activation via the activation of RAC2.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB
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稀释方法 |
WB~~1:1000
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别名 |
Dedicator of cytokinesis protein 2, DOCK2, KIAA0209
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图像 |
All lanes : Anti-DOCK2 Antibody (C-term) at 1:1000 dilution Lane 1: Jurkat whole cell lysates Lane 2: Raji whole cell lysates Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L),Peroxidase conjugated at 1/10000 dilution Predicted band size : 212 kDa Blocking/Dilution buffer: 5% NFDM/TBST. |
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说明书 |
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数量 |
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