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> 抗原抗体、ELISA、WB > 一抗 > Polyclonal Antibodies > fibrillarin / FBL (aa99-110) Antibody (internal region)品牌 |
Leading Biology | 货号 |
APR15957G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality fibrillarin / FBL (aa99-110) antibody (internal region).
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分子量 |
33784 Da
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细胞定位 |
Antigen Cellular Localization:
Nucleus, nucleolus Note=Fibrillar region of the nucleolus
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宿主 |
Goat
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种属反应性 |
Human
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亚型 |
IgG
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通用名 |
FIB1, FLRN
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基因ID |
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UniProt ID |
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功能 |
S-adenosyl-L-methionine-dependent methyltransferase that has the ability to methylate both RNAs and proteins. Involved in pre-rRNA processing by catalyzing the site-specific 2'-hydroxyl methylation of ribose moieties in pre-ribosomal RNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA. Also acts as a protein methyltransferase by mediating methylation of 'Gln-105' of histone H2A (H2AQ104me), a modification that impairs binding of the FACT complex and is specifically present at 35S ribosomal DNA locus (PubMed:24352239).
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形式 |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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别名 |
rRNA 2'-O-methyltransferase fibrillarin, 2.1.1.-, 34 kDa nucleolar scleroderma antigen, Histone-glutamine methyltransferase, FBL, FIB1, FLRN
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图像 |
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说明书 |
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数量 |
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