全部产品分类
品牌 |
Leading Biology | 货号 |
APR11241G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality UBR4 / ZUBR1 antibody (C-Term).
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分子量 |
573841 Da
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细胞定位 |
Antigen Cellular Localization:
Membrane; Multi-pass membrane protein. Cytoplasm. Cytoplasm, cytoskeleton Nucleus. Note=Concentrates at the leading edge of membrane structures involved in actin motility
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宿主 |
Goat
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种属反应性 |
Human
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亚型 |
IgG
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通用名 |
KIAA0462, KIAA1307, RBAF600, ZUBR1
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基因ID |
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UniProt ID |
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功能 |
E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. Together with clathrin, forms meshwork structures involved in membrane morphogenesis and cytoskeletal organization. Regulates integrin-mediated signaling. May play a role in activation of FAK in response to cell-matrix interactions. Mediates ubiquitination of ACLY, leading to its subsequent degradation.
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形式 |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
IHC, E
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别名 |
E3 ubiquitin-protein ligase UBR4, 6.3.2.-, 600 kDa retinoblastoma protein-associated factor, N-recognin-4, Retinoblastoma-associated factor of 600 kDa, RBAF600, p600, Zinc finger UBR1-type protein 1, UBR4, KIAA0462, KIAA1307, RBAF600, ZUBR1
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图像 |
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说明书 |
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数量 |
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