品牌 |
Leading Biology | 货号 |
APR07628G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Dual oxidase 1 antibody (internal region).
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分子量 |
177235 Da
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细胞定位 |
Antigen Cellular Localization:
Apical cell membrane; Multi- pass membrane protein. Note=Localizes to the apical membrane of epithelial cells
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宿主 |
Goat
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种属反应性 |
Human
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亚型 |
IgG
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通用名 |
DUOX, LNOX1, THOX1
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基因ID |
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UniProt ID |
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功能 |
Generates hydrogen peroxide which is required for the activity of thyroid peroxidase/TPO and lactoperoxidase/LPO. Plays a role in thyroid hormones synthesis and lactoperoxidase-mediated antimicrobial defense at the surface of mucosa. May have its own peroxidase activity through its N-terminal peroxidase-like domain.
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总结 |
This antibody is expected to recognise both reported isoforms (NP_059130.2 ; NP_787954.1) which are identical;
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形式 |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
IHC, E
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别名 |
Dual oxidase 1, 1.11.1.-, 1.6.3.1, Large NOX 1, Long NOX 1, NADPH thyroid oxidase 1, Thyroid oxidase 1, DUOX1, DUOX, LNOX1, THOX1
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图像 |
APR07628G (4 μg/ml) staining of paraffin embedded Human Thyroid Gland. Steamed antigen retrieval with Tris/EDTA buffer pH 9, HRP-staining. |
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说明书 |
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数量 |
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