品牌 |
Leading Biology | 货号 |
APR15595G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CTDSP1 antibody (internal region).
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分子量 |
29203 Da
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细胞定位 |
Antigen Cellular Localization:
Nucleus. Note=Colocalizes with RNA polymerase II
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宿主 |
Goat
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种属反应性 |
Human, Mouse
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亚型 |
IgG
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通用名 |
NIF3, NLIIF, SCP1
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基因ID |
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UniProt ID |
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功能 |
Preferentially catalyzes the dephosphorylation of 'Ser- 5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.
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总结 |
This antibody is expected to recognise both reported isoforms (NP_067021 and NP_872580)
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形式 |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC, E
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别名 |
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1, 3.1.3.16, Nuclear LIM interactor-interacting factor 3, NLI-IF, NLI-interacting factor 3, Small C-terminal domain phosphatase 1, SCP1, Small CTD phosphatase 1, CTDSP1, NIF3, NLIIF, SCP1
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图像 |
APR15595G (0.1 μg/ml) staining of Mouse Testis lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
APR15595G (5 μg/ml) staining of paraffin embedded Human Tonsil. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. |
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说明书 |
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数量 |
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