品牌 |
Leading Biology | 货号 |
APR16426G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Goat Anti-VPS37C antibody.
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分子量 |
38659 Da
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细胞定位 |
Antigen Cellular Localization:
Late endosome membrane; Peripheral membrane protein. Note=Probably associates with membranes. Recruited to the plasma membrane by HIV-1
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宿主 |
Goat
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种属反应性 |
Human
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亚型 |
IgG
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通用名 |
PML39
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基因ID |
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UniProt ID |
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功能 |
Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.
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总结 |
VPS37C is a subunit of ESCRT-I (endosomal sorting complex required for transport I), a complex in the class E vacuolar protein sorting (VPS) pathway required for sorting ubiquitinated transmembrane proteins into internal vesicles of multivesicular bodies (Eastman et al., 2005 [PubMed 15509564]).
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形式 |
0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC, E
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别名 |
Vacuolar protein sorting-associated protein 37C, hVps37C, ESCRT-I complex subunit VPS37C, VPS37C, PML39
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图像 |
APR16426G (0.03g/ml) staining of human duodenum lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
APR16426G (3.8 μg/ml) staining of paraffin embedded Human Prostate. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. |
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说明书 |
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数量 |
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