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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Polyclonal Antibodies > Goat Anti-TRPC6 Antibody

Goat Anti-TRPC6 Antibody

货号 货期 规格 / 价格 询价
APR12193G 0.1 mg / ¥4950

Goat Anti-TRPC6 Antibody

品牌

Leading Biology

货号

APR12193G

产品分类

Polyclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Goat Anti-TRPC6 antibody.

分子量

106326 Da

细胞定位

Antigen Cellular Localization: Membrane; Multi-pass membrane protein

宿主

Goat

种属反应性

Mouse

亚型

IgG

通用名

TRP6

基因ID

UniProt ID

功能

Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C. Seems not to be activated by intracellular calcium store depletion.

总结

The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2).

形式

0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

FC, E

别名

Short transient receptor potential channel 6, TrpC6, Transient receptor protein 6, TRP-6, TRPC6, TRP6

说明书

数量

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