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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Polyclonal Antibodies > Goat Anti-PDE11A Antibody

Goat Anti-PDE11A Antibody

货号 货期 规格 / 价格 询价
APR16353G 0.1 mg / ¥4950

Goat Anti-PDE11A Antibody

品牌

Leading Biology

货号

APR16353G

产品分类

Polyclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Goat Anti-PDE11A antibody.

分子量

104752 Da

细胞定位

Antigen Cellular Localization: Cytoplasm, cytosol

宿主

Goat

种属反应性

Human

亚型

IgG

基因ID

UniProt ID

功能

Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides cAMP and cGMP. Catalyzes the hydrolysis of both cAMP and cGMP to 5'-AMP and 5'- GMP, respectively.

总结

The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia. Multiple transcript variants encoding different isoforms have been found for this gene.

形式

0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

WB, E

别名

Dual 3', 5'-cyclic-AMP and -GMP phosphodiesterase 11A, 3.1.4.17, 3.1.4.35, cAMP and cGMP phosphodiesterase 11A, PDE11A

图像

APR16353G (1 μg/ml) staining of Human Prostate lysate (35 μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

说明书

数量

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