全部产品分类
品牌 |
Leading Biology | 货号 |
APR12116G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Goat Anti-H11 / HSP22 antibody.
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分子量 |
21604 Da
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细胞定位 |
Antigen Cellular Localization:
Cytoplasm. Nucleus. Note=Translocates to nuclear foci during heat shock
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宿主 |
Goat
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种属反应性 |
Human
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亚型 |
IgG
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通用名 |
CRYAC, E2IG1, HSP22
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基因ID |
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UniProt ID |
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功能 |
Displays temperature-dependent chaperone activity.
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总结 |
The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.
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形式 |
0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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别名 |
Heat shock protein beta-8, HspB8, Alpha-crystallin C chain, E2-induced gene 1 protein, Protein kinase H11, Small stress protein-like protein HSP22, HSPB8, CRYAC, E2IG1, HSP22
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图像 |
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说明书 |
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数量 |
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