品牌 |
Leading Biology | 货号 |
APR12076G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Goat Anti-AVPR1B antibody.
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分子量 |
46971 Da
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细胞定位 |
Antigen Cellular Localization:
Cell membrane; Multi-pass membrane protein.
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宿主 |
Goat
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种属反应性 |
Human
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亚型 |
IgG
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通用名 |
AVPR3, VPR3
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基因ID |
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UniProt ID |
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功能 |
Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system.
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总结 |
The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. A spliced antisense transcript of this gene has been reported but its function is not known.
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形式 |
0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC, E
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别名 |
Vasopressin V1b receptor, V1bR, AVPR V1b, AVPR V3, Antidiuretic hormone receptor 1b, Vasopressin V3 receptor, AVPR1B, AVPR3, VPR3
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图像 |
APR12076G (5 μg/ml) staining of paraffin embedded Human Anterior Pituitary Gland. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
APR12076G (0.5 μg/ml) staining of Human Amygdala lysate (35 μg protein in RIPA buffer) in lane A and AF1129a (0.05 μg/ml) staining of Rat Brain lysate (35 μg protein in RIPA buffer) in lane B . Primary incubation was 1 hour. Detected by chemiluminescence. |
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说明书 |
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数量 |
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