全部产品分类
品牌 |
Leading Biology | 货号 |
AMM04856G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Goat Anti-ABCD3 antibody.
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分子量 |
75476 Da
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细胞定位 |
Antigen Cellular Localization:
Peroxisome membrane; Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441, ECO:0000269|PubMed:10704444}
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宿主 |
Goat
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种属反应性 |
Human
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亚型 |
IgG
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通用名 |
PMP70, PXMP1
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基因ID |
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UniProt ID |
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功能 |
Probable transporter. The nucleotide-binding fold acts as an ATP-binding subunit with ATPase activity.
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总结 |
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein likely plays an important role in peroxisome biogenesis. Mutations have been associated with some forms of Zellweger syndrome, a heterogeneous group of peroxisome assembly disorders. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
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形式 |
0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC, E
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别名 |
ATP-binding cassette sub-family D member 3, 70 kDa peroxisomal membrane protein, PMP70, ABCD3, PMP70, PXMP1
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图像 |
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说明书 |
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数量 |
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