全部产品分类
品牌 |
Leading Biology | 货号 |
APR12013G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality GDNF antibody.
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分子量 |
23662 Da
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细胞定位 |
Antigen Cellular Localization:
Secreted.
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宿主 |
Rabbit
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种属反应性 |
Human
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靶点 |
GDNF
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亚型 |
Rabbit IgG
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基因ID |
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UniProt ID |
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功能 |
Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake.
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总结 |
Glial cell line-derived neurotrophic factor (GDNF) has been identified as a potent neurotrophic factor that enhances survival of midbrain dopaminergic neurons. GDNF is a glycosylated, disulfide-bonded homodimer. It promotes the survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake. On the basis of these findings, it has been s μggested that GDNF may play a role in the treatment of Parkinson’s disease, which is marked by progressive degeneration of midbrain dopaminergic neurons.
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形式 |
Liquid
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC, IP
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别名 |
neurotrophic factor GDNF, GDNF, Glial cell line-derived neurotrophic factor, Astrocyte-derived trophic factor; ATF
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说明书 |
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数量 |
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