全部产品分类
品牌 |
Leading Biology | 货号 |
AMM05330G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Heme Oxygenase-1 antibody.
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分子量 |
32819 Da
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细胞定位 |
Antigen Cellular Localization:
Microsome. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side
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宿主 |
Rabbit
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种属反应性 |
Human, Mouse, Rat, Rabbit, Hamster, Monkey
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靶点 |
Heme Oxygenase-1
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亚型 |
Rabbit IgG
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通用名 |
HO, HO1
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基因ID |
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UniProt ID |
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功能 |
Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. Under physiological conditions, the activity of heme oxygenase is highest in the spleen, where senescent erythrocytes are sequestrated and destroyed. Exhibits cytoprotective effects since excess of free heme sensitizes cells to undergo apoptosis.
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总结 |
Heme oxygenase-1 (HO-1) or HSP32 is the inducible isoform of heme oxygenase which catalyzes the NADPH, O2 and cytochrome P450 reductase dependent oxidation of heme to carbon monoxide, iron and biliverdin that is immediately reduced to bilirubin. To date, three heme oxygenase isoforms HO-1, HO-2 and HO-3 have been identified.
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形式 |
Liquid
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC, IP
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别名 |
HMOX1 , HO , HO-1 , HO1 , OTTHUMP00000028925 , bK286B10 , EC 1.14.99.3
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图像 |
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说明书 |
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数量 |
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