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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Polyclonal Antibodies > CaMKII Antibody

CaMKII Antibody

货号 货期 规格 / 价格 询价
APG02343G 100 μg / ¥4950

CaMKII Antibody

品牌

Leading Biology

货号

APG02343G

产品分类

Polyclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CaMKII antibody.

分子量

54088 Da

细胞定位

Antigen Cellular Localization: Cell junction, synapse, presynaptic cell membrane. Cell junction, synapse Note=Postsynaptic lipid rafts.

宿主

Rabbit

种属反应性

Human, Mouse, Rat

靶点

CaMKII

亚型

Rabbit IgG

通用名

CAMKA, KIAA0968

基因ID

UniProt ID

功能

CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity (By similarity).

总结

CaMKII is a member of calcium/calmodulin-activated kinase, functioning in neural synaptic stimulation and T-cell receptor signaling. CaMKII has catalytic and regulatory domains. The binding of Ca++/calmodulin to its regulatory domain releases its autoinhibitory effect and activates the kinase. The activated CaMKII further autophosphorylates itself at Thr286 to render the kinase constitutively active.

形式

Liquid

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

WB

别名

CAMK2A , CAMKA , KIAA0968, EC 2.7.11.17

说明书

数量

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