品牌 |
Leading Biology | 货号 |
AMM05390G |
产品分类 |
Monoclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality MYST1 antibody.
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分子量 |
53kDa
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细胞定位 |
Antigen Cellular Localization:
Nucleus. Chromosome
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宿主 |
Mouse
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种属反应性 |
Human
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克隆号 |
8C4C4
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亚型 |
IgG2b
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通用名 |
MOF, MYST1
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基因ID |
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UniProt ID |
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功能 |
Histone acetyltransferase which may be involved in transcriptional activation. May influence the function of ATM. As part of the MSL complex it is involved in acetylation of nucleosomal histone H4 producing specifically H4K16ac. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. That activity is less specific than the one of the MSL complex. Can also acetylate TP53/p53 at 'Lys-120'.
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形式 |
Liquid. In PBS containing 0.02% sodium azide.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC, ICC, E
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稀释方法 |
WB~~1/500 - 1/2000
IHC~~1/200 - 1/1000
IF~~1/200 - 1/1000
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别名 |
Histone acetyltransferase KAT8, 2.3.1.48, Lysine acetyltransferase 8, MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1, MYST-1, hMOF, KAT8, MOF, MYST1
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图像 |
Figure 1: Western blot analysis using MYST1 mouse mAb against Hela (1), HepG2 (2) and SMMC-7721 (3) cell lysate.
Figure 2: Immunohistochemical analysis of paraffin-embedded human esophageal squamous cell carcinoma (A), normal esophagus epithelium (B), rectum adenocarcinoma (C), lung squamous cell carcinoma (D), breast infiltrating carcinoma (E), and breast infiltrating carcinoma (F) tissues, showing nuclear localization using MOF/MYST1 mouse mAb with DAB staining.
Figure 3: Confocal immunofluorescence analysis of Eca 109 cells using MOF/MYST1 mouse mAb (green), showing nuclear localization. |
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说明书 |
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数量 |
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