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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Polyclonal Antibodies > Microtubule Associated Protein 2 (MAP2) Antibody

Microtubule Associated Protein 2 (MAP2) Antibody

货号 货期 规格 / 价格 询价
AMM06395G 100 μl / ¥4950

Microtubule Associated Protein 2 (MAP2) Antibody

品牌

Leading Biology

货号

AMM06395G

产品分类

Polyclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Microtubule Associated Protein 2 (MAP2) antibody.

分子量

280 KDa

宿主

Chicken

种属反应性

Bovine, Human, Mouse, Rat

靶点

Bovine MAP2 isolated from brain by the GTP microtubule cycling method.

基因ID

UniProt ID

总结

Microtubules are 25nm diameter protein rods found in most kinds of eukaryotic cells. They are polymerized from a dimeric subunit made of one a subunit and one b tubulin subunit. Microtubules are associated with a family of proteins called microtubule associated proteins (MAPs), which includes the protein τ (tau) and a group of proteins referred to as MAP1, MAP2, MAP3, MAP4 and MAP5 (Kindler & Gardner 1994). MAP2 is made up of two ~280kDa apparent molecular weight bands referred to as MAP2a and MAP2b. A third lower molecular weight form, usually called MAP2c, corresponds to a pair of protein bands running at ~70kDa on SDS-PAGE gels. All these MAP2 forms are derived from a single gene by alternate transcription, and all share a C-terminal sequence which includes either three or four microtubule binding peptide sequences, which are very similar to those found in the related microtubule binding protein τ (tau). MAP2 isoforms are expressed only in neuronal cells and specifically in the perikarya and dendrites of these cells. MAP2 has been recently shown to be the specific receptor for the neurosteroid pregnenolone (Fontaine-Lenore V. et al., 2006).

形式

Total IgY fraction

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

WB, IF

稀释方法

WB~~ 1:20000 IF~~ 1:2500

别名

Microtubule-associated protein 2, MAP-2, MAP2

图像

Western blot of rat cortex lysate showing specific immunolabeling of the ~280k MAP2protein.

Mixed neuron/glial cultures. The perikarya and dendrites of neurons are stronglyand specifically stained with the MAP2 antibody (red). Cell nuclei are visualized with DAPI DNA stain.

说明书

数量

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