全部产品分类
品牌 |
Leading Biology | 货号 |
APR08990G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality PDGF-BB antibody.
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分子量 |
27283 Da
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细胞定位 |
Antigen Cellular Localization:
Secreted. Note=Released by platelets upon wounding
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宿主 |
Rabbit
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种属反应性 |
Human
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靶点 |
PDGF-BB
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亚型 |
Rabbit IgG
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通用名 |
PDGF2, SIS
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基因ID |
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UniProt ID |
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功能 |
Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. Required for normal blood vessel development, and for normal development of kidney glomeruli. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFA (By similarity).
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总结 |
Human Platelet Derived Growth Factor (PDGF) is a potent mitogen for a wide range of cell types including fibroblasts, smooth muscle and connective tissue. PDGF is composed of a dimer of two chains termed the A chain and B chain, and thus can be present as AA or BB homodimers or as an AB heterodimer. Human PDGF-BB is a 14-18.0 kDa protein containing 109 amino acid residues.
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形式 |
200 μg (0.5 mg/ml) affinity purified rabbit anti-human PDGF-BB polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol and 0.01% thimerosal.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB
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别名 |
platelet-derived growth factor subunit B
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图像 |
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说明书 |
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数量 |
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