全部产品分类
品牌 |
Leading Biology | 货号 |
APR08179G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality LDHA antibody (Center).
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分子量 |
36689 Da
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细胞定位 |
Antigen Cellular Localization:
Cytoplasm.
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宿主 |
Rabbit
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种属反应性 |
Human, Rat, Monkey, Pig, Bovine
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靶点 |
LDHA
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亚型 |
Rabbit IgG
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基因ID |
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UniProt ID |
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总结 |
L-Lactate dehydrogenase A chain (LDHA) is a member of the LDH/MDH superfamily and LDH family. It catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. LDHA is localized primarily in muscle tissue and is part of the lactate dehydrogenase family. Mutations in LDHA have been linked to exertional myoglobinuria. LDH1 is decreased in essential thrombocythemia. LDHA is induced through a non-genomic pathway of estrogen action. Reduction in LDH-A activity results in stimulation of mitochondrial respiration and decrease of mitochondrial membrane potential. Mutations in LDHA have been associated with in LDHA are the cause of glycogen storage disease type 11 (GSD11) which is a metabolic disorder that results in exertional myoglobinuria, pain, cramps and easy fatigue.
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形式 |
Liquid. In PBS containing 0.02% sodium azide.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC, FC
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别名 |
LDHA; L-lactate dehydrogenase A chain; Cell proliferation-inducing gene 19 protein; LDH muscle subunit; Renal carcinoma antigen NY-REN-59.
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说明书 |
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数量 |
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