全部产品分类
品牌 |
Leading Biology | 货号 |
APR15993G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality FKBP52/Hsp56 antibody.
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分子量 |
51572 Da
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细胞定位 |
Antigen Cellular Localization:
Cytoplasm, cytosol. Mitochondrion. Nucleus. Cytoplasm, cytoskeleton Note=Shuttles from mitochondria to nucleus; co-localizes in mitochondria with the glucocorticoid receptor.
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宿主 |
Rabbit
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种属反应性 |
Mouse, Rat
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靶点 |
FKBP52/Hsp56
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亚型 |
Rabbit IgG
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通用名 |
Fkpb52
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基因ID |
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UniProt ID |
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功能 |
Immunophilin protein with PPIase and co-chaperone activities. Component of steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90). May play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors between cytoplasm and nuclear compartments. The isomerase activity controls neuronal growth cones via regulation of TRPC1 channel opening. Acts also as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly. May have a protective role against oxidative stress in mitochondria.
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总结 |
FKBP52 (also known as FKBP4, Hsp56, FK506 binding protein 4, p52, FKBP59) is a 55kDa peptidyl-propyl isomerase. FKBP52 catalyzes the transition between cis- and trans- proline residues which is important in immunoregulation and proper protein folding and trafficking. FKBP52 may involve in the intracellular trafficking of hetero-oligomeric forms of the steroid hormone receptors.
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形式 |
Liquid
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB
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别名 |
FKBP4, Hsp56, FK506 binding protein 4, p52, FKBP59
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说明书 |
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数量 |
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