品牌 |
Leading Biology | 货号 |
APR07490G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality Cytochrome P450 antibody.
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分子量 |
56849 Da
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细胞定位 |
Antigen Cellular Localization:
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein
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宿主 |
Rabbit
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种属反应性 |
Human, Mouse, Rat, Dog
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靶点 |
Cytochrome p450
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亚型 |
Rabbit IgG
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通用名 |
CYP2E
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基因ID |
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UniProt ID |
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功能 |
Metabolizes several precarcinogens, drugs, and solvents to reactive metabolites. Inactivates a number of drugs and xenobiotics and also bioactivates many xenobiotic substrates to their hepatotoxic or carcinogenic forms.
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总结 |
Cytochrome P450 is mainly found in liver, and can metabolize a wide range of compounds such as organic solvents, acetaminophen, dimethylnitrosoamine and aliphatic alcohol, which have certain toxicological effects in humans. Ethanol-induced cytochrome P450 IIE1 is considered to be one of the major causes of oxidative stress in the liver following ethanol treatment.
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形式 |
Liquid
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB
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别名 |
AHH , AHRR, CYP1A1 , CP11 , CYP1, P1-450, CYPIA1, P450-C, , P450DX, P450-P1
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图像 |
Western blot analysis of cytochrome P450 using Rat kidney tissue lysate. |
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说明书 |
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数量 |
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