品牌 |
Leading Biology | 货号 |
AMM06343G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality MATH1/HATH1/ATOH1 antibody (N-term).
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分子量 |
38160 Da
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细胞定位 |
Antigen Cellular Localization:
Nucleus.
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宿主 |
Rabbit
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种属反应性 |
Human, Mouse
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免疫原 |
78-109 aa
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靶点 |
This MATH1/HATH1/ATOH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 78-109 amino acids from the N-terminal region of human MATH1/HATH1/ATOH1.
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亚型 |
Rabbit Ig
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通用名 |
ATH1, BHLHA14
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基因ID |
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UniProt ID |
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功能 |
Transcriptional regulator. Activates E box-dependent transcription in collaboration with TCF3/E47, but the activity is completely antagonized by the negative regulator of neurogenesis HES1. Plays a role in the differentiation of subsets of neural cells by activating E box-dependent transcription (By similarity).
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总结 |
ATOH1 belongs to the basic helix-loop-helix (BHLH) family of transcription factors. It activates E-box dependent transcription along with E47.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:1000
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别名 |
Protein atonal homolog 1, Class A basic helix-loop-helix protein 14, bHLHa14, Helix-loop-helix protein hATH-1, hATH1, ATOH1, ATH1, BHLHA14
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图像 |
All lanes : Anti-ATOH1 (Human N-term) at 1:2000 dilution Lane 1: Hela whole cell lysate Lane 2: Jurkat whole cell lysate Lane 3: HepG2 whole cell lysate Lane 4: NIH/3T3 whole cell lysate Lane 5: human fetal brain lysate Lane 6: mouse brain lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 38 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Western blot analysis of ATOH1 (arrow) using rabbit polyclonal ATOH1 Antibody (Human N-term) (Cat. AMM06343G). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the ATOH1 gene (Lane 2) (Origene Technologies). |
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说明书 |
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数量 |
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