品牌 |
Leading Biology | 货号 |
APR13583G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality STMN2 antibody (N-term).
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分子量 |
20828 Da
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细胞定位 |
Antigen Cellular Localization:
Cytoplasm. Cytoplasm, perinuclear region. Cell projection, growth cone Membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, axon. Golgi apparatus. Endosome. Cell projection, lamellipodium Note=Associated with punctate structures in the perinuclear cytoplasm, axons, and growth cones of developing neurons. SCG10 exists in both soluble and membrane-bound forms. Colocalized with CIB1 in neurites of developing hippocampal primary neurons (By similarity). Colocalized with CIB1 in the cell body, neuritis and growth cones of neurons. Colocalized with CIB1 to the leading edge of lamellipodia.
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宿主 |
Rabbit
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种属反应性 |
Human, Mouse, Rat
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靶点 |
This STMN2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 36-69 amino acids from the N-terminal region of human STMN2.
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亚型 |
Rabbit Ig
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通用名 |
SCG10, SCGN10
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基因ID |
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UniProt ID |
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功能 |
Regulator of microtubule stability. When phosphorylated by MAPK8, stabilizes microtubules and consequently controls neurite length in cortical neurons. In the developing brain, negatively regulates the rate of exit from multipolar stage and retards radial migration from the ventricular zone (By similarity).
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总结 |
Regulator of microtubule stability. When phosphorylated by MAPK8, stabilizes microtubules and consequently controls neurite length in cortical neurons. In the developing brain, negatively regulates the rate of exit from multipolar stage and retards radial migration from the ventricular zone (By similarity).
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, FC, IHC-P, E
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稀释方法 |
IHC-P~~1:25
FC~~1:25
WB~~1:1000
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别名 |
Stathmin-2, Superior cervical ganglion-10 protein, Protein SCG10, STMN2, SCG10, SCGN10
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图像 |
Immunohistochemical analysis of paraffin-embedded H. liver section using STMN2 Antibody (N-term)( APR13583G). APR13583G was diluted at 1:25 dilution. A undiluted biotinylated goat polyvalent antibody was used as the secondary, followed by DAB staining.
Flow cytometric analysis of SH-SY5Y cells using STMN2 Antibody (N-term)(green, APR13583G) compared to an isotype control of rabbit IgG(blue). APR13583G was diluted at 1:25 dilution. An Alexa Fluor? 488 goat anti-rabbit lgG at 1:400 dilution was used as the secondary antibody.
Western blot analysis of lysates from U-87 MG, SH-SY5Y cell line, human brain, mouse brain, rat brain tissue lysate (from left to right), using STMN2 Antibody (N-term)( APR13583G). APR13583G was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 35ug per lane. |
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说明书 |
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数量 |
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