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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Polyclonal Antibodies > PIP5KL1 Antibody (N-term)

PIP5KL1 Antibody (N-term)

货号 货期 规格 / 价格 询价
AMM07198G 100 μl / ¥4950

PIP5KL1 Antibody (N-term)

品牌

Leading Biology

货号

AMM07198G

产品分类

Polyclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PIP5KL1 antibody (N-term).

分子量

44572 Da

细胞定位

Antigen Cellular Localization: Cytoplasm. Membrane. Note=Localized to large cytoplasmic vesicular structures.

宿主

Rabbit

种属反应性

Human

免疫原

57-86 aa

靶点

This PIP5KL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 57-86 amino acids from the N-terminal region of human PIP5KL1.

亚型

Rabbit Ig

基因ID

UniProt ID

功能

May act as a scaffold to localize and regulate type I PI(4)P 5-kinases to specific compartments within the cell, where they generate PI(4,5)P2 for actin nucleation, signaling and scaffold protein recruitment and conversion to PI(3,4,5)P3.

总结

PIP5KL1 is a phosphoinositide kinase-like protein thatlacks intrinsic lipid kinase activity but associates with type IPIPKs (see PIP5K1A; MIM 603275) and may play a role in localizationof PIPK activity (Chang et al., 2004 [PubMed 14701839]).[suppliedby OMIM].

形式

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

WB, IHC-P, IF, E

稀释方法

WB~~1:1000 IHC-P~~1:50~100 IF~~1:10~50

别名

Phosphatidylinositol 4-phosphate 5-kinase-like protein 1, PI(4)P 5-kinase-like protein 1, PtdIns(4)P-5-kinase-like protein 1, PIP5KL1

图像

Western blot analysis of lysates from 293,K562,PC-3 cell line (from left to right),using PIP5KL1 Antibody (N-term)(Cat. AMM07198G).AMM07198G was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody.Lysates at 35ug per lane.

PIP5KL1 Antibody (N-term) (Cat. AMM07198G)immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PIP5KL1 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Confocal immunofluorescent analysis of PIP5KL1 Antibody (N-term)( AMM07198G) with U-251MG cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).

说明书

数量

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