品牌 |
Leading Biology | 货号 |
APR11755G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
|
产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality DLL4 antibody (C-term).
|
||
分子量 |
74605 Da
|
||
细胞定位 |
Antigen Cellular Localization:
Membrane; Single-pass type I membrane protein
|
||
宿主 |
Rabbit
|
||
种属反应性 |
Human
|
||
免疫原 |
625-652 aa
|
||
靶点 |
This DLL4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 625-652 amino acids from the C-terminal region of human DLL4.
|
||
亚型 |
Rabbit Ig
|
||
基因ID |
|||
UniProt ID |
|||
功能 |
Involved in the Notch signaling pathway as Notch ligand. Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Essential for retinal progenitor proliferation is required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types. During spinal cord neurogenesis, inhibits V2a interneuron fate.
|
||
总结 |
DLL4 is a homolog of the Drosophila delta gene. The delta gene family encodes Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain.
|
||
形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
|
||
储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
|
||
应用 |
WB, IHC-P, FC, E
|
||
稀释方法 |
WB~~1:1000
IHC-P~~1:50~100
FC~~1:10~50
|
||
别名 |
Delta-like protein 4, Drosophila Delta homolog 4, Delta4, DLL4
|
||
图像 |
Western blot analysis of DLL4 Antibody (C-term) (Cat. APR11755G) in K562 cell line lysates (35ug/lane). DLL4 (arrow) was detected using the purified Pab.
DLL4 Antibody (C-term) (Cat. APR11755G) IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the DLL4 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
DLL4 Antibody (C-term) (Cat. APR11755G) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
||
说明书 |
|||
数量 |
|
||
| 选择 | 品牌 | 货号 | 产品名称 | 规格 | 分类 | 研究领域 | 说明书 | 数量 | 目录价 | |
| 1 | Leading Biology | APR05963G | EGFR Antibody (Y1092) | 100 μl | Polyclonal Antibodies |
|
¥4950.00 | 订购 询价 | ||
| 2 | Leading Biology | APR03116G | BRCA1 Antibody (aa1847-1863) | 100 μl | Polyclonal Antibodies |
|
¥4950.00 | 订购 询价 | ||
| 3 | Leading Biology | AMM05633G | Bombesin Receptor 2 (extracellular) Antibody | 50 μl | Polyclonal Antibodies |
|
¥6950.00 | 订购 询价 | ||
| 4 | Leading Biology | APR10986G | AP3B1 Antibody (aa2-14) | 50 μg | Polyclonal Antibodies |
|
¥4950.00 | 订购 询价 | ||
| 5 | Leading Biology | APR11512G | Bestrophin-1 (extracellular) Antibody | 50 μl | Polyclonal Antibodies |
|
¥6950.00 | 订购 询价 | ||
| 6 | Leading Biology | APG01407G | A3 Adenosine Receptor Antibody | 50 μl | Polyclonal Antibodies |
|
¥6950.00 | 订购 询价 |
关注安诺伦新浪微博
关注安诺伦公众号
微信扫描二维码,随时随地与小诺亲密接触,精彩活动,劲爆优惠,触手可得!

销售-华东区