全部产品分类
品牌 |
Leading Biology | 货号 |
AMR09896G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SGIP1 antibody (N-term).
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分子量 |
89109 Da
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细胞定位 |
Antigen Cellular Localization:
Membrane, clathrin-coated pit; Peripheral membrane protein; Cytoplasmic side
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宿主 |
Rabbit
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种属反应性 |
Human, Mouse
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免疫原 |
1-30 aa
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靶点 |
This SGIP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human SGIP1.
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亚型 |
Rabbit Ig
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基因ID |
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UniProt ID |
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功能 |
May function in clathrin-mediated endocytosis. Has both a membrane binding/tubulating activity and the ability to recruit proteins essential to the formation of functional clathrin-coated pits. Has a preference for membranes enriched in phosphatidylserine and phosphoinositides and is required for the endocytosis of the transferrin receptor. May also bind tubulin. May play a role in the regulation of energy homeostasis (By similarity).
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总结 |
SGIP1 functions as an endocytic protein that affects signaling by receptors in neuronal systems involved in energy homeostasis via its interaction with endophilins (see SH3GL3; MIM 603362) (Trevaskis et al., 2005 [PubMed 15919751] and Uezu et al., 2007 [PubMed 17626015]).
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, E
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稀释方法 |
WB~~1:1000
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别名 |
SH3-containing GRB2-like protein 3-interacting protein 1, Endophilin-3-interacting protein, SGIP1
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图像 |
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说明书 |
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数量 |
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