全部产品分类
品牌 |
Leading Biology | 货号 |
APG02771G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CROT antibody (N-term).
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分子量 |
70178 Da
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细胞定位 |
Antigen Cellular Localization:
Peroxisome.
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宿主 |
Rabbit
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种属反应性 |
Human, Mouse
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免疫原 |
49-79 aa
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靶点 |
This CROT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 49-79 amino acids from the N-terminal region of human CROT.
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亚型 |
Rabbit Ig
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通用名 |
COT
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基因ID |
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UniProt ID |
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功能 |
Beta-oxidation of fatty acids. The highest activity concerns the C6 to C10 chain length substrate. Converts the end product of pristanic acid beta oxidation, 4,8-dimethylnonanoyl- CoA, to its corresponding carnitine ester.
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总结 |
CROT encodes a member of the carnitine/choline acetyltransferase family. The encoded protein converts 4,8-dimethylnonanoyl-CoA to its corresponding carnitine ester. This transesterification occurs in the peroxisome and is necessary for transport of medium- and long- chain acyl-CoA molecules out of the peroxisome to the cytosol and mitochondria. The protein thus plays a role in lipid metabolism and fatty acid beta-oxidation. Alternatively spliced transcript variants have been described.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
FC, IHC-P, WB, E
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稀释方法 |
FC~~1:10~50
IHC-P~~1:50~100
WB~~1:1000
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别名 |
Peroxisomal carnitine O-octanoyltransferase, COT, CROT, COT
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图像 |
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说明书 |
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数量 |
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