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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Polyclonal Antibodies > MTNR1A Antibody (Center)

MTNR1A Antibody (Center)

货号 货期 规格 / 价格 询价
AMM06502G 100 μl / ¥4950

MTNR1A Antibody (Center)

品牌

Leading Biology

货号

AMM06502G

产品分类

Polyclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MTNR1A antibody (Center).

分子量

39375 Da

细胞定位

Antigen Cellular Localization: Cell membrane; Multi-pass membrane protein.

宿主

Rabbit

种属反应性

Human

免疫原

209-239 aa

靶点

This MTNR1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 209-239 amino acids from the Central region of human MTNR1A.

亚型

Rabbit Ig

基因ID

UniProt ID

功能

High affinity receptor for melatonin. Likely to mediates the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity.

总结

MTNR1A encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This receptor is a G-protein coupled, 7-transmembrane receptor that is responsible for melatonin effects on mammalian circadian rhythm and reproductive alterations affected by day length. The receptor is an integral membrane protein that is readily detectable and localized to two specific regions of the brain. The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin.

形式

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

WB, FC, E

稀释方法

WB~~1:1000 FC~~1:10~50

别名

Melatonin receptor type 1A, Mel-1A-R, Mel1a receptor, MTNR1A

图像

Western blot analysis of MTNR1A Antibody (Center) (Cat. AMM06502G) in CEM cell line lysates (35ug/lane). MTNR1A (arrow) was detected using the purified Pab.

MTNR1A Antibody (Center) (Cat. AMM06502G) flow cytometric analysis of CEM cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

说明书

数量

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