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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Polyclonal Antibodies > ITGA2 Antibody (C-term)

ITGA2 Antibody (C-term)

货号 货期 规格 / 价格 询价
APR08060G 100 μl / ¥4950

ITGA2 Antibody (C-term)

品牌

Leading Biology

货号

APR08060G

产品分类

Polyclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ITGA2 antibody (C-term).

分子量

129295 Da

细胞定位

Antigen Cellular Localization: Membrane; Single-pass type I membrane protein

宿主

Rabbit

种属反应性

Human

免疫原

1023-1049 aa

靶点

This ITGA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1023-1049 amino acids from the C-terminal region of human ITGA2.

亚型

Rabbit Ig

通用名

CD49B

基因ID

UniProt ID

功能

Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix.

总结

ITGA2 id a protein that belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane glycoproteins composed of a distinct alpha chain and a common beta chain. They are found on a wide variety of cell types including, T cells, fibroblasts and platelets. Integrins are involved in cell adhesion and also participate in cell-surface mediated signalling.

形式

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

WB, E

稀释方法

WB~~1:1000

别名

Integrin alpha-2, CD49 antigen-like family member B, Collagen receptor, Platelet membrane glycoprotein Ia, GPIa, VLA-2 subunit alpha, CD49b, ITGA2, CD49B

图像

Anti-ITGA2 Antibody (C-term) at 1:1000 dilution + A431 whole cell lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 129 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

Western blot analysis of ITGA2 Antibody (C-term) (Cat. APR08060G) in MDA-MB231 cell line lysates (35ug/lane). ITGA2 (arrow) was detected using the purified Pab.

说明书

数量

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