全部产品分类
品牌 |
Leading Biology | 货号 |
AMM05462G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality UNC13B antibody (Center).
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分子量 |
180679 Da
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细胞定位 |
Antigen Cellular Localization:
Cytoplasm. Membrane; Peripheral membrane protein. Cell membrane. Cell junction, synapse Note=Localized to synapses. Translocated to the plasma membrane in response to phorbol ester binding (By similarity).
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
1062-1091 aa
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靶点 |
This UNC13B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1062-1091 amino acids from the Central region of human UNC13B.
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亚型 |
Rabbit Ig
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通用名 |
UNC13
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基因ID |
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UniProt ID |
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功能 |
Plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. Is involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity- depending refilling of readily releasable vesicle pool (RRP). Essential for synaptic vesicle maturation in a subset of excitatory/glutamatergic but not inhibitory/GABA-mediated synapses (By similarity).
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总结 |
UNC13B plays a role in vesicle maturation during exocytosis as a target of the diacylglycerol second messenger pathway. It is involved in neurotransmitter release by acting in synaptic vesicle priming prior to vesicle fusion and participates in the activity-depending refilling of readily releasable vesicle pool (RRP). It is essential for synaptic vesicle maturation in a subset of excitatory/glutamatergic but not inhibitory/GABA-mediated synapses (By similarity).
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, FC, E
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稀释方法 |
WB~~1:1000
FC~~1:10~50
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别名 |
Protein unc-13 homolog B, Munc13-2, munc13, UNC13B, UNC13
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图像 |
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说明书 |
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数量 |
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