品牌 |
Leading Biology | 货号 |
APR13147G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality RPGRIP1 antibody (Center).
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分子量 |
146682 Da
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细胞定位 |
Antigen Cellular Localization:
Cell projection, cilium. Note=Situated between the axonemal microtubules and the plasma membrane {ECO:0000250|UniProtKB:Q9EPQ2}
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
530-557 aa
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靶点 |
This RPGRIP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 530-557 amino acids from the Central region of human RPGRIP1.
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亚型 |
Rabbit Ig
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基因ID |
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UniProt ID |
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功能 |
May function as scaffolding protein. Required for normal location of RPGR at the connecting cilium of photoreceptor cells. Required for normal disk morphogenesis and disk organization in the outer segment of photoreceptor cells and for survival of photoreceptor cells.
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总结 |
RPGRIP1 is a photoreceptor protein that interacts with retinitis pigmentosa GTPase regulator protein and is a key component of cone and rod photoreceptor cells.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P, FC, E
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稀释方法 |
WB~~1:1000
IHC-P~~1:50~100
FC~~1:10~50
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别名 |
X-linked retinitis pigmentosa GTPase regulator-interacting protein 1, RPGR-interacting protein 1, RPGRIP1
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图像 |
Western blot analysis of RPGRIP1 Antibody (Center) (Cat. APR13147G) in HL-60, K562, MDA-MB435, Jurkat cell line lysates (35ug/lane). RPGRIP1 (arrow) was detected using the purified Pab.
Formalin-fixed and paraffin-embedded human breast carcinoma reacted with RPGRIP1 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
RPGRIP1 Antibody (Center) (Cat. APR13147G) flow cytometry analysis of MDA-MB231 cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
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说明书 |
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数量 |
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