全部产品分类
品牌 |
Leading Biology | 货号 |
APR15569G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality COTL1 antibody (C-term).
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分子量 |
15945 Da
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细胞定位 |
Antigen Cellular Localization:
Cytoplasm, cytoskeleton. Nucleus membrane; Peripheral membrane protein
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
115-142 aa
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靶点 |
This COTL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 115-142 amino acids from the C-terminal region of human COTL1.
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亚型 |
Rabbit Ig
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通用名 |
CLP
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基因ID |
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UniProt ID |
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功能 |
Binds to F-actin in a calcium-independent manner. Has no direct effect on actin depolymerization. Acts as a chaperone for ALOX5 (5LO), influencing both its stability and activity in leukotrienes synthesis.
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总结 |
COTL1 is one of the numerous actin-binding proteins which regulate the actin cytoskeleton. This protein binds F-actin, and also interacts with 5-lipoxygenase, which is the first committed enzyme in leukotriene biosynthesis.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IHC-P, FC, E
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稀释方法 |
WB~~1:1000
IHC-P~~1:50~100
FC~~1:10~50
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别名 |
Coactosin-like protein, COTL1, CLP
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图像 |
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说明书 |
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数量 |
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