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当前位置:首页 > 抗原抗体、ELISA、WB > 一抗 > Polyclonal Antibodies > SGK2 Antibody (C-term)

SGK2 Antibody (C-term)

货号 货期 规格 / 价格 询价
AMM07769G 100 μl / ¥4950

SGK2 Antibody (C-term)

品牌

Leading Biology

货号

AMM07769G

产品分类

Polyclonal Antibodies

研究领域

产品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SGK2 antibody (C-term).

分子量

47604 Da

细胞定位

Antigen Cellular Localization: Cytoplasm. Nucleus

宿主

Rabbit

种属反应性

Human

免疫原

395-426 aa

靶点

This SGK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 395-426 amino acids from the C-terminal region of human SGK2.

亚型

Rabbit Ig

基因ID

UniProt ID

功能

Serine/threonine-protein kinase which is involved in the regulation of a wide variety of ion channels, membrane transporters, cell growth, survival and proliferation. Up- regulates Na(+) channels: SCNN1A/ENAC, K(+) channels: KCNA3/Kv1.3, KCNE1 and KCNQ1, amino acid transporter: SLC6A19, glutamate transporter: SLC1A6/EAAT4, glutamate receptors: GRIA1/GLUR1 and GRIK2/GLUR6, Na(+)/H(+) exchanger: SLC9A3/NHE3, and the Na(+)/K(+) ATPase.

总结

SGK2, a Ser/Thr protein kinase, is similar to serum- and glucocorticoid-induced protein kinase (SGK), but this gene product is not induced by serum or glucocorticoids. Expression is induced in response to signals that activate phosphatidylinositol 3-kinase, which is also true for SGK.

形式

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

储存条件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

应用

WB, IHC-P, E

稀释方法

WB~~1:1000 IHC-P~~1:50~100

别名

Serine/threonine-protein kinase Sgk2, Serum/glucocorticoid-regulated kinase 2, SGK2

图像

Western blot analysis of anti-SKG2 Pab (Cat. AMM07769G) in placenta lysate. SKG2 (arrow) was detected using purified Pab. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.

说明书

数量

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