品牌 |
Leading Biology | 货号 |
APG02896G |
产品分类 |
Polyclonal Antibodies | 研究领域 |
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产品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CYP4A11 (4A22) antibody (C-term).
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分子量 |
59348 Da
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细胞定位 |
Antigen Cellular Localization:
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein
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宿主 |
Rabbit
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种属反应性 |
Human
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免疫原 |
407-435 aa
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靶点 |
This CYP4A11 (4A22) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 407-435 amino acids from the C-terminal region of human CYP4A11 (4A22).
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亚型 |
Rabbit Ig
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通用名 |
CYP4A2
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基因ID |
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UniProt ID |
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功能 |
Catalyzes the omega- and (omega-1)-hydroxylation of various fatty acids such as laurate, myristate and palmitate. Has little activity toward prostaglandins A1 and E1. Oxidizes arachidonic acid to 20-hydroxyeicosatetraenoic acid (20-HETE).
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总结 |
CYP4A11 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and hydroxylates medium-chain fatty acids such as laurate and myristate.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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储存条件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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应用 |
WB, IF, E
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稀释方法 |
WB~~1:1000
IF~~1:10~50
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别名 |
Cytochrome P450 4A11, 20-hydroxyeicosatetraenoic acid synthase, 20-HETE synthase, CYP4AII, CYPIVA11, Cytochrome P-450HK-omega, Cytochrome P450HL-omega, Fatty acid omega-hydroxylase, Lauric acid omega-hydroxylase, CYP4A11, CYP4A2
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图像 |
Western blot analysis of anti-CYP4A11 (4A22) Antibody (C-term) (Cat. APG02896G) in NCI-H460 cell line lysates (35ug/lane).CYP4A11(arrow) was detected using the purified Pab.
Confocal immunofluorescent analysis of CYP4A11 (4A22) Antibody (C-term)( APG02896G) with NCI-H460 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).DAPI was used to stain the cell nuclear (blue). |
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说明书 |
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数量 |
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